Among these 358 IgM ELISA positives, the mean age of the patients was 29.7 years with female preponderance (61.7%), fever was the most common (100%) clinical characteristic followed by nausea (50.6%) with thrombocytopenia in 74.09%, presence of eschar was observed in 3.1% patients. The gene discussed is CD40LG; the disease is Thrombocytopenia.