The recruitment of Endothelial Progenitor Cells (EPCs) to sites of tumor angiogenesis is also a multistep process, and although JAM-C was demonstrated in several studies to play a role in angiogenesis and tumor growth [18,30,31,36], none of the studies addressed the role of JAM-C in the context of endothelial progenitor cell recruitment to tumor angiogenesis. Here, JAM3 is linked to neoplasm.