RPS6KB2 and breast carcinoma: Although the involvement of S6K2 in breast cancer metastasis has not been studied yet, S6K2 was shown to be a direct target of miR-193a-3p, which suppresses lung metastasis; downregulation of S6K2 by miR-193a-3p was shown to be a potential mechanism by which miR-193a-3p inhibited migration, invasion and EMT in non-small cell lung cancer [55].