A recent analysis of 279 Head and Neck Squamous Cell Carcinoma (HNSCC) tumors by The Cancer Genome Atlas (TCGA) identified roughly thirty percent of HNSCC patients have genomic amplifications of Fas-Associated Death Domain (FADD), with a subset of these patients also having amplifications in BIRC2/cIAP1 or BIRC3/cIAP2 [74,75]. Here, BIRC2 is linked to head and neck squamous cell carcinoma.