Flow immunophenotyping showed that blasts expressed CD4, CD7, CD11b, CD38, CD34, CD33, and cCD3.<h4>Conclusion</h4>It is the first T-cell blast of CML case with coexisting p210 and p190 as well as additional chromosome translocations. The gene discussed is CD38; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.