In ovarian cancer, miR‐339 inhibited the tumor progress by directly regulating NACC1 and Bcl6 while miR‐339 regulated the metastasis of colorectal cancer via targeting PRL‐1.23, 24 LncRNA RP11‐81H3.2 might function as a ceRNA and sponge the miR‐339. The gene discussed is NACC1; the disease is colorectal cancer.