GPER1 and gastric cancer: Analysis of the KMPLOT database shows that high GPR30 expression leads to poor prognosis in gastric cancer, implicating the potential role of GPR30 in gastric cancer.27 In this study, we aimed to investigate the role of GPR30 in the formation of cisplatin resistance in GC cells and to explore the potential of GPR30 as a therapeutic target for improving the efficacy of chemotherapy in GC.