Nevertheless, the absence of an impact of ABO blood type on factor VIII levels in our series of patients with portal hypertension may provide an additional explanation for ABO blood type not affecting PVT prevalence, since increases in factor VIII are considered as a main factor linking ABO and VTE in the general population,48 as well as an important contributor to the hypercoagulability paralleling liver disease progression.49, 50. Here, ABO is linked to portal hypertension.