For example, lncRNA IGF2AS was found to be down‐regulated in NSCLC tumour tissue and was closely related to the overall survival of patients; IGF2AS therefore is an anticancer lncRNA and an ideal target for drug development.26 In the current study, F63 seems to belong to cancer suppressor lncRNA, as we found the most important gene for angiogenesis—VEGFA was up‐regulated significantly after inhibiting F63 by siRNA not only at transcription level but also at translation level. The gene discussed is IGF2-AS; the disease is cancer.