It might also be possible that the occurrence of semantic impairments become more prominent in MAPT in a later stage of the disease [28], as anterior medial temporal lobe atrophy progresses, an area that has been linked to semantic naming errors in for instance Alzheimer’s disease [2] and is known to also deteriorate bilaterally in patients with a MAPT mutation [28]. The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.