GRN mutations often lead to a prominent asymmetrical pattern of atrophy in the frontal, temporal and parietal lobes, and are associated with behavioral deficits, apraxia and language disorders, most frequently resulting in a clinical diagnosis of bvFTD or non-fluent variant PPA (nfvPPA) and is often accompanied by parkinsonism [21, 29]. This evidence concerns the gene GRN and behavioral variant of frontotemporal dementia.