CCL24 and nonpapillary renal cell carcinoma: Because CCL24 has been reported to usually activate downstream signaling pathways via C–C motif chemokine receptor 3 (CCR3)18 and because the most credible functional partner of CCL24 was also predicted as CCR3 by the STRING database (Supplementary Fig. S3i), we next examined whether blocking CCR3 could alleviate the gankyrin/CCL24-increased growth and progression of ccRCC.