Moreover, the effects of gankyrin overexpression on the invasion or migration abilities of ccRCC cells were examined through invasion or migration assays, respectively, and the results showed that the numbers of invaded and migrated ccRCC cells were higher in the gankyrin-overexpressing ccRCC cells compared with the control cells (Fig. 1c, d). This evidence concerns the gene PSMD10 and nonpapillary renal cell carcinoma.