PSMD10 and nonpapillary renal cell carcinoma: The ccRCC cell lines (786-O and 769-P) were stably transfected with gankyrin (Supplementary Fig. S1a), and the proliferation activity of ccRCC cells was then determined through Cell Counting Kit-8 (CCK-8) proliferation experiments, which showed that the gankyrin-overexpressing ccRCC cells exhibited increased cell proliferation compared with the control cells (Fig. 1a).