The analysis of compound–compound target network and PPI network of compound targets displayed that PIK3CG, CASP3, BCL2, CASP8, and MMP1 might be the key targets of the YCHD in hepatitis C. The module analysis found that the YCHD has the potential to influence varieties of biological pathways that play an important role in the pathogenesis of hepatitis C, including the TNF signaling pathway, Ras signaling pathway, etc. Twelve pathways were obtained by KEGG pathway enrichment analysis, including those that involve the PI3K-Akt signaling pathway, FoxO signaling pathway, pathways in cancer, etc. This evidence concerns the gene CASP8 and cancer.