ACC haplotype containing the IL-10 -1082A allele was associated with PEX (P = 0.02, OR = 5.76, 95% CI = 5.17–24.49), PEXG (P = 0.006, OR = 7.54, 95% CI = 6.62–30.76) and POAG (P = 0.003, OR = 8.11, 95% CI = 7.13–33.15), suggesting that IL-10 -1082A allele plays an important role in susceptibility to PEX, PEXG and POAG eye disorders. The gene discussed is IL10; the disease is open-angle glaucoma.