The results from qPCR and Western blot analysis displayed that both the mRNA and protein levels of NDPK-B and SK4 channels were higher in ARVC-hiPSC-CMs than those in donor-hiPSC-CMs (Figure 1), suggesting possible roles of NDPK-B or SK4 in pathogenesis of ARVC. This evidence concerns the gene KCNN4 and arrhythmogenic right ventricular cardiomyopathy.