NQO1 and cancer: A widely accepted mechanism in cancer chemoprevention by dietary phytochemicals is through the induction of antioxidant and cytoprotective systems, such as reduced glutathione (GSH), and the activity of the phase 2 enzymes GST and NQO1, among others, through the activation of Nrf2 (NF-E2-related factor 2) signaling pathways [41].