Furthermore, blood adiponectin concentrations in the treated patients showing no clinical improvement (active disease) were statistically (p < 0.05) higher as compared to adiponectinaemia in the healthy children and the treated patients with inactive JIA, while serum resistin levels in the treated patients with the active disease corresponded (p > 0.05) to concentrations in the remaining evaluated groups. This evidence concerns the gene RETN and juvenile idiopathic arthritis.