We recorded insignificant relationships between COMP with leptin (r = 0.35, p = 0.326) and resistin (r = 0.25, p = 0.168) but significant relationships with adiponectin (r = −0.64, p = 0.01) in patients with the treated JIA whose clinical condition had not stabilized (active disease). The gene discussed is LEP; the disease is juvenile idiopathic arthritis.