The following genes were up-regulated: OXTR (coding for oxytocin receptor), ITGA3 (coding for integrin subunit alpha 3), HRH1 (coding for histamine receptor H1), EIF4A3 (coding for eukaryotic translation initiation factor 4A3), ID2 (coding for inhibitor of DNA binding 2), and HOMER2 (coding for Homer scaffold protein 2), while expression of B2M (coding for β-2-microglobulin) and INSR (coding for insulin receptor) was down-regulated in most of MPS types. The gene discussed is HOMER2; the disease is mucopolysaccharidosis.