Primary cutaneous CD30+ lymphoproliferative disorder (CD30CLPD) consists of lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (pcALCL) at benign and malignant ends of the spectrum, respectively.[1] LyP is characterized clinically by spontaneously regressing papules and nodules (usually less than 2 cm diameter) and is divided into five subtypes A to E based on histo-immunopathologic findings. This evidence concerns the gene TNFRSF8 and lymphoproliferative syndrome.