Meanwhile our findings of TB correlations with Hb and Hct are consistent with prior reports.[45,46] With respect to the potential relationship between mild hemolysis and bilirubin levels, prior reports have been largely speculative with little statistical confirmation.[29–33] Our finding of a negative correlation between RBC lifespan and serum TB suggests strongly that RBC turnover rate is an important factor affecting serum bilirubin levels in patients with GS. This evidence concerns the gene GSTM1 and Gerstmann syndrome.