FBXO32 and Cachexia: Other studies buttress the view that increased FoxO signalling and the activation of the transcription factors nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐κB), MuRF1, and muscle atrophy F‐box (MAFbx) in skeletal muscle play major roles during cachexia onset and progression.10 MuRF1 and MAFbx are essentially involved in muscle atrophy development.