Inducers of MuRF1 and MAFbx expression are tumour necrosis factor (TNF), IL‐6, and IL‐1, and NF‐κB appears to be the most important regulator of MuRF1 and MAFbx expression in the skeletal muscle.6 Lima et al. 11 (University of São Paulo, São Paulo, Brazil) showed in C57BL/6 wild‐type mice and IL‐1 receptor knockout mice (B6.129S7‐il1r tm1/mx/J) that weight loss was significantly higher in wild‐type mice relative to IL‐1R−/− mice after accounting for tumour mass (P = 0.0056). This evidence concerns the gene TRIM63 and neoplasm.