Given the inconsistency of results from studies among different races, this studyaims to evaluate four SNPs (rs2167270 (G>A), rs7799039 (A>G), rs6588147(G>A), and rs1137100 (G>A)) in the LEP and LEPR genes in patients with CAD ina North Chinese population to provide a frame of reference for relatedevaluations. This evidence concerns the gene LEP and coronary artery disorder.