MiR‐203 expression was down‐regulated in NSCLC and negatively correlated with clinical tumour‐node‐metastasis (TNM) stages.14 Jiang et al demonstrated that HCP5 repressed miR‐203 acting as a molecular sponge, stabilized Snail and Slug, and in turn, promoted the invasion of lung cancer cells.15 Taken together, HCP5 up‐regulated the expression of Snail and Slug by sponging miR‐203 and activated the TGF‐β/SMAD signal pathway promoting metastasis of NSCLC. This evidence concerns the gene SNAI2 and non-small cell lung carcinoma.