Cai et al found HMMR‐AS1 functioned as a ceRNA of miR‐138, and the high expression of miR‐138 caused the repression of its endogenous target SIRT6.23 SIRT6 is a direct target of miR‐138, and knockdown of SIRT6 in NSCLC cells could increase the paclitaxel sensitivity.24 HMMR‐AS1 could be considered as a potential target for the diagnosis and treatment of NSCLC. Here, SIRT6 is linked to non-small cell lung carcinoma.