LncRNA small nucleolar RNA host gene 1 (SNHG1) was found overexpressed in diverse cancers, such as liver carcinoma, prostate cancer and NSCLC.91, 92, 93 Zhang et al discovered that SNHG1 could promote ZEB1 protein expression by inhibiting the expression of TAp63, which was one of the isoforms of p63.94 It confirmed that SNHG1 might induce the NSCLC metastasis through activating the TAp63/ZEB1 signalling pathway. This evidence concerns the gene ZEB1 and Familial prostate cancer.