POU6F2 and Abnormal emotional state: More specifically, genome-wide association studies have identified POU6F2 risk variants associated with psychological distress (Koshimizu et al. 2019), feeling emotionally hurt (Nagel et al. 2018), schizophrenia (Goes et al. 2015), autism (Anney et al. 2010), educational attainment (Lee et al. 2018; Okbay et al. 2016) and intelligence (Hill et al. 2018; Davies et al. 2018).