Moreover, PAK1 plays a major role in diseases, such as nervous system disorders including Alzheimer (Ma et al., 2012) and cancer development including malignant progression (Holm et al., 2006; Kamai et al., 2010; Ong et al., 2011; Ye and Field, 2012; Radu et al., 2014). The gene discussed is PAK1; the disease is cancer.