MDM2 and breast carcinoma: It inhibited the interaction between MDM2 and p53 peptide with an IC50 of 0.91 ± 0.12 μM, and it suppressed proliferation of five breast cancer lines: MCF-7 (IC50 2.5 μM), ZR-75-1 (3.3 μM), BT-474 (35.5 μM), MDA-MB-231 (47.3 μM), and SKBR-3 (41.8 μM).