ABCD1 and Mental deterioration: For example, the Addison-only form of X-ALD has no neurological impact, while the cerebral form of X-ALD often causes severe sensory loss, motor function impairment, cognitive decline, and death.<h4>Results</h4>A case of adult onset adrenomyeloneuropathy (AMN) and a novel <i>ABCD1</i> cause VLCFAs to build up in various tissues and bodily fluids, resulting in a disorder called X-linked adrenoleukodystrophy (X-ALD).