CBL and infection: Cell cycle and chromatin-expression regulators, such as ubiquitination of proteins (mediated by tnip1 or cbl), methylation (via downregulation of euchromatic histone-lysine N-methyltransferase 1L that methylates the lysine-9 position of histone H3 and tags it for transcriptional repression) or uridylation of mRNAs appear significantly and exclusively regulated in brainless animals (with or without infection).