Since cognitive decline can be due to neurodegenerative pathologies or independent of them, we examined the associations between miR-484 and miR-197-3p and cognitive decline adjusting for all the measured neurodegenerative pathologies (i.e., global AD pathology, gross infarcts, microscopic infarcts, TDP-43, hippocampal sclerosis, CAA, atherosclerosis, and Lewy bodies) and sex, age at death, PMI, RIN, study, and cell-type proportions. Here, TARDBP is linked to Mental deterioration.