Similar to neuroblastoma 25, oral squamous cell carcinoma, lung cancer 26, and breast cancer 27, downregulation of LGALS1 had been shown to reduce the viability and proliferation of both SiHa and C33A cervical cancer cells, whereas LGALS1 overexpression significantly enhanced the viable and proliferative rates of SiHa cells in the present study. This evidence concerns the gene LGALS1 and lung cancer.