Pu Y et al. provided evidence after conducted a case-control study involving 319 patients with cervical cancer and 424 healthy control women, illustrating that among 2 polymorphisms of IL1A gene, the allele I of rs3783553 may related with reduced cervical carcinogenesis risk, reduced susceptibility advancing to stage II-III or developing non-squamous cell carcinoma 11. The gene discussed is IL1A; the disease is cervical carcinoma.