Other studies have shown that expression of GSK3β can inhibit the expression of miR-183 through the β-Catenin/TCF/LEF-1 pathway in human gastric cancer cells, while β-Catenin/TCF/LEF-1 binds to the promoter of miR-183 and thereby activates the transcription of miR-183 8. The gene discussed is HNF4A; the disease is gastric cancer.