KEGG analysis of the downregulated target genes of miRNA-93 revealed that EPHA7, CFL2, and DPYSL2 are significantly enriched in axon guidance pathway (P = 0.000129528), and PPP1R3B and SLC2A4 are significantly attached to insulin resistance pathway (p = 0.001718367), we hypothesized that the activated axon guidance pathway and the insulin resistance pathway may be responsible for the downregulation of miRNA-93 in BC. The gene discussed is DPYSL2; the disease is breast cancer.