CHEK1 and cancer: KEGG analysis of the upregulated target genes of miRNA-195 revealed that CHEK1, CCNE1, and CDC25A are significantly enriched in the cell cycle pathway (p = 0.00000888), and CHEK1, MYB, and WNT7A are enriched in HTLV-I infection pathway (p = 0.000077), CCNE1, KIF23, and CDC25A enriches microRNAs in cancer (p = 0.000117168), CHEK1 and CCNE1 enriches p53 signaling pathway (p = 0.000241969).