Thus, elevated total (>1,000 kU/L) and specific anti-Aspergillus IgE can be observed in the setting of STAT3 deficiency, not only in patients with ABPA-like presentation as evidenced by Duréault et al. (11), but also in other forms of STAT3 deficiency-related pulmonary aspergillosis as evidenced here. Here, STAT3 is linked to aspergillosis.