TBCE and hepatocellular carcinoma: In this review, we will summarize current knowledge about hepatic macrophages in pathogenesis of alcoholic liver disease (ALD), non-alcoholic steatohepatitis (NASH), hepatitis B virus/hepatitis C virus (HBV/HCV), and hepatocellular carcinoma (HCC) with a particular focus on KCs and monocyte-derived macrophages.