IRAK4 and Chronic mucocutaneous candidosis: In some cases, other variants in the same molecule have even been associated with other PIDs, such as chronic mucocutaneous candidiasis for IL-17F, recurrent pyogenic infections for IRAK4, and autoinflammatory fever syndromes for TNFAIP3, TNFRSF1A, and PLCG2, although mostly in patients homozygous for the given variant.