In particular, Hajje et al. showed that propil-thiouracil-induced-hypothyroidism increased the plasma concentration of inflammatory markers C reactive protein (CRP) and cytokines (e.g., TNF-a and IL6) as well inflammatory gene markers (e.g., TGF-β1 and cTGF and Il1 and Mcp1). Here, CRP is linked to hypothyroidism.