In the p53−/− tumor-suppressor background, survival analysis by Kaplan–Meier revealed that Rassf10 knockout animals (n = 77; Rassf10+/−/Rassf10−/−) had a reduced survival rate vs. Rassf10+/+ animals (n = 24, Fig. 3a, Table 2). Here, RASSF10 is linked to neoplasm.