In the spinal cord, WT-infected mice had higher levels of Il6, Tnf, Ccl2, and Ccl5 mRNAs at 2 or 4 days after infection, while Il1β was highest in Y114A at 2 and 6 days (P < 0.01 versus G32S, P < 0.0001 versus Y114A). This evidence concerns the gene TNF and infection.