Platelet-derived growth factor receptor β (PDGFRβ)-expressing pericytes are responsible for post-stroke fibrotic repair within infarct areas; therefore, we examined peri-infarct neural reorganization and functional recovery after permanent middle cerebral artery occlusion (pMCAO) using pericyte-deficient <i>Pdgfrb<sup>+/-</sup></i> mice. This evidence concerns the gene PDGFRB and stroke disorder.