VIM and renal cell carcinoma: Both in RCC tissues and RCC cell lines where miR-124 and miR-203 were downregulated, we observed reduced expression of E-cadherin and β-catenin (epithelial marker) as well as induced level of N-catenin and vimentin (mesenchymal markers), indicating that loss of both miRNAs significantly increased the migration and proliferation of ccRCC cells via regulating the key elements in EMT.