The results showed that TNF-α 238G/A locus A had no significant association with CAD susceptibility: the allelic model (A vs. G) (OR:1.088, 95% CI:0.950–1.244); the homozygote model (AA vs. GG) (OR:1.506, 95% CI:0.835–2.715); the dominant model (AA + GA vs. GG) (OR: 1.072, 95% CI:0.931–1.235); the regressive model (AA vs. The gene discussed is TNF; the disease is coronary artery disorder.