The results showed that TNF-α 308G/A locus A had no significant association with CAD susceptibility: the allelic model (A vs. G) (OR:1.047, 95% CI:0.973–1.126); the homozygote model (AA vs. GG) (OR:1.106,95% CI:0.888–1.377); the dominant model (AA + GA vs. GG) (OR: 1.046,95% CI:0.963–1.136); the regressive model (AA vs.GA + GG) (OR: 1.102,95% CI: 0.886–1.370); the heterozygote model (GA vs. GG) (OR: 1.037,95%CI:0.950–1.131). This evidence concerns the gene TNF and coronary artery disorder.