Furthermore, some autoAbs induce inflammation by causing uncontrolled neutrophil activation, such as the anti-neutrophil cytoplasmic antibody (ANCA) in ANCA-associated vasculitis, or causing inflammation at the site of autoantibody binding, such as autoAbs targeting myosin in myocarditis or the anti-cyclic citrullinated peptide antibody in rheumatoid arthritis (RA) [3]. This evidence concerns the gene MYH14 and rheumatoid arthritis.