NCAM1 and neuroblastoma: Moreover, reported drivers of neuroblastoma metastasis and other crucial determinants of bone marrow metastasis, such as loss of CD44 [14] or increase in CXCR4 [15], NCAM [16], VCAM1 [17], several integrin subunits [18] as well as GD2 gangliosides [19], were all not differentially expressed on the surface of LAN-1-PT vs. LAN-1-BM cells (Figure S1, Supplementary Materials).