Additionally, we examined the efficacy of the IL-27 cytokines modified at the C-terminus in a STAT1-luc reporter assay, where co-transfection of IL-27ns vector augmented the STAT1 activity in both TC2R and Ras/Myc murine prostate adenocarcinoma cells (RM1) cell lines (Figure 1d, p < 0.05). The gene discussed is STAT1; the disease is prostate adenocarcinoma.