Prostate cancer cells TRAMPC2-Ras (TC2R) were transfected with control empty vector (plasmid DNA pcDNA3.1), or the same backbone vector containing control IL-27 with a non-specific peptide, or the targeted form of IL-27 (IL-27pepL, targeted to the IL-6Rα), as described in the Materials and Methods section. Here, IL27 is linked to prostate cancer.