Although we observed a significant (p < 0.01) increase in hepatic gene expression of the regulators of fibrosis, transforming growth factor beta (TGF-β), and tissue inhibitor of metalloproteinases-1 (TIMP-1), in the WD group, we did not confirm their increased expression at the protein level (Figure 5 a–d). Here, TGFB1 is linked to Wilson disease.