Then, miR‐223‐3p possibly acts as a tumor promoter and enhances tumor cells metastasis via downregulation of SLC4A4 in renal cell carcinoma.27 MiR‐223‐3p inhibition relieves lung cancer development by targeting TGFBR3.28 MiR‐223‐3p inhibits tumor cell apoptosis and proliferation in testicular germ cell tumors.29 But the function of miR‐223‐3p in colon cancer is not fully studied. Here, TGFBR3 is linked to colonic neoplasm.