INS and diabetic ketoacidosis: Further, 75% (18/24) of patients started with diabetic ketoacidosis (DKA) and all patients had elevated glycated hemoglobin, with 10 patients having significantly lower or no detectable C‐peptide levels, suggesting faster islet β‐cell failure.22 Once diagnosed, it is necessary to initiate insulin therapy immediately and give the basic combined meal insulin, and if necessary, also give a subcutaneous insulin pump to control blood glucose level.