MAPT and Mental deterioration: Fourth, due to limited data availability, we did not include tau-PET, which has been recently shown to be a good predictor of future cognitive decline in AD.15 However, we included measures of tau-related pathology (ie, CSF), which have been previously shown to correlate with the level of tau-PET uptake50 and to predict future cognitive decline.9 Nevertheless, inclusion of tau-PET in the SVR model may improve prediction of cognitive decline.