In this context, different categories of T22‐GFP‐H6 ArtIBs were implanted subcutaneously (SC) in a CXCR4+ colorectal cancer mouse model, releasing fluorescent material from the implantation point, followed by selective uptake by a remote CXCR4+ tumor, with specific kinetics for each ArtIB type. This evidence concerns the gene CXCR4 and colorectal cancer.