The top 20 changed pathways predicted by the differently expressed genes were listed in Table S5 (Supporting Information), which suggested there are a panel of key pathways that are affected by LINC00152 suppression, including colorectal cancer signaling pathway, adherent junction, and apoptosis, etc. GSEA on the mRNA profiles change revealed positive associations between LINC00152 and multiple gene sets, including gene sets involved in cell cycle, metastasis, cytoskeleton, and vascular endothelial growth factor A signaling (Figure 3B). Here, VEGFA is linked to colorectal cancer.