YAP1 and cancer: Interestingly, NF2 is a sensor in the cell–cell contact inhibition of the Hippo signaling.19, 20 We thus investigated whether cell density change could modulate LINC00152 expression in the previous conducted model of different culture cell confluence (i.e., from 10% to 100%).16 Figure 2H demonstrates that the expression of NF2 was gradually increased along with cancer cell density arising, while LINC00152 and YAP1 expression was decreased when cell density was arising.